Even Dupieux was surprised. "When you think Manson, you think death, skulls and baby-burning," he says. "I was picturing a rock star. I was not picturing a really smart artist. But no! The guy is funny. He just has, like, a really positive and fun energy, which I love. Every good artist is still a kid, even if that sounds corny."

Manson's acted before. He played a drag star in Party Monster and a porn star in Lost Highway. At nineteen, he even had an uncredited two-frame cameo in the original 21 Jump Street. "I had a glorious, glorious, glorious bleach-tipped mullet and a slight tan," says Manson. "I walked right behind Johnny Depp playing skee-ball." But for now, he's still gotta convince people he can make audiences laugh.

"I always polarize any room," he admits. "I can't shut up. Usually it's because people think I'm drunk, and maybe it's because I am. But when you meet somebody who's funny like Danny McBride and you riff off them, it's cool because it's a different kind of collaboration than what I do in music."

Up next, Manson is reteaming with Dupieux for an upcoming comedy where he'll play a fashion photographer he describes as "a combination of Kenny Powers and Karl Lagerfeld." No matter where their partnership takes them, Dupieux will always have a permanent place in Manson's life. Literally — his wrist is tattooed with the motto of Rubber: "No reason." His buddy Depp got one to match. Says Manson, "When people ask us why, we say 'No reason.'" Hey, loving oddball art-house comedies is reason enough.

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