The 7 Best Hangover Supplements [2021 List]

Waking up with a hangover is part and parcel of a social lifestyle. And let’s face it, they get worse with age.

So-called hangover supplements are popular natural remedies to this problem. Packed with vitamins, minerals, and herbal extracts, they are formulated to support recovery after drinking alcohol.

But with literally dozens of different brands to chose from, it can be hard to know which one works the best.

In this complete guide, we take a closer look at the best products on the market right now.

Our top picks

This list prioritizes the best hangover supplements with proven track records, top reviews, and good safety profiles.

We've only included products made from natural ingredients that do not contain stimulants or medicines.

Before getting into it, we have to mention that supplements are not a substitute for sensible drinking habits. In other words, they are not "hangover cures" and you still need to drink in moderation alongside plenty of water to have the best chance of waking up with less of a hangover.

With that said, here’s a breakdown of our favorites…

1. AfterDrink

AfterDrink takes the #1 spot for us in our list of best hangover supplements.

That's because it contains 100% natural ingredients including dihydromyricetin, milk thistle, prickly pear extract, ginseng, ginger, high dose B vitamins, NAC, and many more (we cover how all the ingredients work in more detail at the end of this review). Furthermore, AfterDrink is made in a GMP-certified facility (Good manufacturing practice) in the US.

Overall, it stands out from others because it has a comprehensive formulation with high-quality ingredients that covers all angles.

Why we like AfterDrink

  • Effective hangover supplement
  • All-natural ingredients
  • Premium product
  • Lots of positive reviews and testimonials online
  • Fully vegan
  • Bulk discounts are available, giving you the opportunity to save money
  • Made in the USA

How do you use AfterDrink?

Take 3 capsules before drinking alcohol and 3 more after your last drink.

Here’s what real customers are saying about AfterDrink:

“Great product. Helped to ease the hangover after a heavy night out with friends."

“I was really surprised to find that these actually work! I usually get really horrible hangovers that make me feel like I have to spend the entire day doing nothing, but these helped take the edge off for sure!”

Makes my hangover symptoms half as bad as they usually are which is more than I could ask for.”

Click here for the lowest price

2. DripDrop

Although not specifically designed as a hangover supplement, DripDrop is a great hydration booster that tackles one of the main causes of a hangover. We all know that dehydration is a big part of hangovers and drinking the right amount of water can be difficult to judge.

DripDrop contains the perfect balance of salts and sugar which enhances optimum rehydration. In fact, combining DripDrop with one of the other hangover prevention products on this list gives the best results.

Why we like DripDrop
  • Hydration super booster
  • Additional vitamin C, magnesium, and zinc
  • Easy to carry packaging
  • Comes in several flavors

How do you use DripDrop?

Simply open a sachet and mix it with water. For best results, drink one sachet after your last drink and another as soon as you wake up in the morning.

Here's what real customers are saying about DripDrop

"This is the best tasting electrolyte packet I’ve ever had! Hands down the best hangover cure"

"This stuff we would mix it with our beer topped with a frozen margarita and BLAM. Hydrated. 70% less of a hangover"

Click here for the lowest price

3. Morning Recovery

Morning recovery drink is probably one of the most well-known hangover supplements on the market and you may have come across one of their ads on social media. Founded by an ex-Tesla engineer, Morning recovery has expanded into a whole range of different wellness products outside of their flagship drink.

Why we like Morning Recovery

  • One of the first hangover drink supplements on the market
  • Available in different flavors
  • Great selection of ingredients
  • Multi-pack offers

How do you use Morning Recovery?

Drink one full bottle after your last drink. You can also use it as a mixer for your last cocktail of the night.

Here's what real customers are saying about Morning Recovery

"We are a little older so it doesn't take much to get a hangover, so these really help!"

"It is pricey but totally worth it. Feel great the next day."

Click here for the lowest price

4. Flyby

Flyby takes #4 spot in this best hangover supplements list. It's a well-rounded product and they've sold thousands of bottles to happy customers over the years. It includes most of the key ingredients we like to see and has a strong reputation and brand.

Why we like Flyby

  • Available in different sizes.
  • A wide range of reviews online.
  • No artificial additives.
  • Good value for money.

How do you use Flyby?

3 capsules before drinking and another 3 straight after your last drink (Same dosing as AfterDrink)

Here’s what real customers are saying about Flyby:

“I have used FlyBy for about six months now and not only have I noticed it alleviates the murky grogginess one gets after a glass of wine too many.”

I have tried a few of the "hangover cure" supplements on the market today and they all seem to be pretty comparable. Flyby will be my go to since it is the most cost effective and has similar results to the more expensive options.

Click here for the lowest price

5. Cheers

Looking for high doses of dihydromyricetin? Well, Cheers may be the hangover supplement for you with a whopping 1200mg in a 3 capsule serving.

Why we like Cheers

  • Highest dihydromyricetin dose (1200mg).
  • Clear ingredients table.
  • Feel 50% better money-back guarantee.
  • Strong brand.

How do you use Cheers?

They recommend taking between 2-4 pills after your last drink.

Here’s what real customers are saying about Cheers:

“I definitely think these work. I'm less frequently hungover, even if only sleeping better so I'm less groggy the next day.”

“I used to get terrible, debilitating nausea after drinking. I have been using Cheers capsules and the mix and wake up like a new person.”

Click here for the lowest price

6. Detoxx

Detoxx is on the cheaper end of the hangover supplement market providing a great entry-level product that is good value for money. At just under $20 a bottle, Detoxx contains a decent selection of ingredients including NAC, B-vitamins, and prickly pear among others.

Why we like Detoxx

  • Value for money
  • Best choice if on a tight budget
  • Decent selection of ingredients

How do you use Detoxx?

Take 3 capsules before drinking alcohol and repeat after your last drink (same as AfterDrink and Flyby)

Here's what real customers are saying about Detoxx

"Seems to work for me. Obviously not a cure all, but with water before bed, I always end up better the next day."

"This stuff really works"

Click here for the lowest price

7. Ease by Toniiq

Toniiq is one of the first-ever brands in the hangover supplement category. Their main product Ease features a lean formulation with only 3 ingredients: Reishi mushroom, Dihydromyricetin, and Milk thistle. The bulk of the dose goes toward Reishi mushroom which has gained popularity in recent years in the wellness world.

Why we like Ease by Toniiq

  • Simple formulation
  • Cheap
  • Natural ingredients

How do you use Ease by Toniiq?

Take 3 capsules before and after drinking alcohol

Here's what real customers are saying about Toniiq

Ease relieves most of the disturbing symptoms of hangover even when I take less than suggested or take it only after drinking rather than before and after.

I get pretty brutal hangovers & so far using these, I've only experienced minor symptoms compared to staying in bed all day.

Click here for the lowest price

Do hangover supplements work?

It’s the first question that everybody asks. Do hangover supplements actually work?

The answer is: it depends on how you use them and what your goals are.

They work by boosting antioxidant levels, support alcohol metabolism, and the liver's ability to detox after drinking.

But the positive effects are seen with sensible drinking habits. By that we mean, drinking in moderation and taking all the usual precautions such as keeping well hydrated and avoiding eating on an empty stomach.

A quick search online will show thousands upon thousands of positive hangover supplement reviews and many people swear by their effectiveness.

On the other hand, if your aim is to get black-out drunk, then hangover supplements are not for you. They are not miracle cures.

Ingredients to look out for

It’s worth knowing a bit about the actual ingredients to understand how they help with hangovers. That way, you can make an informed decision when it comes to choosing which product to buy. After all, it's the ingredients formula that determines how effective the supplement will be.

A quick heads up before we continue - there are no good research studies into natural hangover remedies. Therefore, the benefits reported below shouldn’t be treated as proven facts.

With that said, there are a few small studies with interesting results:

Prickly pear
Prickly pear fruits come from cactus trees and are packed full of polyphenols. Polyphenols are plant-based compounds that are natural antioxidants. A small study of 64 people showed taking prickly pear before drinking reduced hangover severity.

Dihydromyricetin (DHM)
This active compound is extracted from the oriental raisin tree fruits. It’s been used traditionally for centuries as a natural remedy. Animal studies have shown it can potentially support alcohol metabolism.

Milk thistle
Milk thistle is a common ingredient you’ll find in hangover prevention supplements. you’ll also find it in many liver health supplements because it’s known to have antioxidant and anti-inflammatory properties.

Korean ginseng
A small study of 25 men showed that taking ginseng helped reduced inflammation associated with a hangover.

N-Acetyl-Cysteine (NAC)
NAC is an amino acid that is the precursor to glutathione. In other words, your liver uses NAC as one of the building blocks to make glutathione. And glutathione is a powerful antioxidant that neutralizes free radicals.

Alpha-Lipoic acid
Your body produces alpha-lipoic acid naturally, but it’s also found in a variety of foods and dietary supplements. It’s an organic compound that acts as a powerful antioxidant in the body.

The B group vitamins are essential cofactors in the metabolism of all the food and drink we consume. Vitamin B1, B2, B3, and B6 frequently feature in hangover supplements.

Vitamin C
Everyone knows about vitamin C and its importance for the immune system. Aside from this, it’s also a natural antioxidant.

This list includes some, but not all, ingredients you can expect to see in hangover prevention supplements. It's always a good idea to do your own research before investing your money.

How to make the most out of hangover supplements

We’ve mentioned before that hangover supplements are not miracle cures. That means you’ll still need to do everything else in your power to prevent waking up with a bad hangover.

Aside from (obviously) drinking less alcohol, there are a few other things you should also consider:

  1. Rehydration salts
    One of the best ways of supercharging the effectiveness of your hangover supplement is to combine it with rehydration salts. These are commonly used for diarrheal illnesses or endurance sports but are also great for hangover-related dehydration. That's we included DripDrop as the rehydration mix in our list above.

    Oral rehydration solutions contain a mix of minerals and sugars that facilitate optimum water absorption from the gut.

    Drinking a glass of water with rehydration salts alongside your supplements at the end of your night will give you the best chance of waking up without the usual morning haze.

  2. Don’t drink on an empty stomach
    Your mum was right, don't drink on an empty stomach!

    Alcohol is absorbed much faster when your stomach is empty. This leads to spikes in blood alcohol concentrations and added pressure on your liver. It’s a surefire way of waking up with a hangover.

    Here’s the catch.

    It doesn’t really matter what you eat before drinking alcohol. Studies have shown that most food types (carbohydrates, protein, fat) will slow down alcohol absorption. In fact, it’s a great idea to take your first dose with a meal to cover that base.

  3. Stick to lighter colored drinks

    Did you know that it’s actually been shown that darker-colored drinks cause worse hangovers?

    Drinks like red wine and whiskey contain higher amounts of congeners. These are by-products formed when alcohol is fermented and aged. On one hand, they are responsible for the taste we all love. On the other hand, congeners react with your cells and fuel inflammation.

It’s been shown in studies that high congener alcohol frequently gives test subjects more severe hangovers. That’s not to say that lighter-colored spirits like vodka and gin won’t. Clearly, if you drink enough of any type of alcohol, you will have a hangover.

Where to buy hangover supplements

There are several hangover prevention supplements available to buy on Amazon, GNC, and even at Walmart.

From our experience, we always find great deals when going direct to brand websites. In addition, by joining their mailing lists, you can get big seasonal discounts.

Are they safe?

The hangover supplements we’ve reviewed in this article are all-natural and don’t contain medicines or banned substances.

By their nature, plant extracts and the other compounds found in supplements can cause adverse reactions now and again. Especially if you have an unknown allergy to a particular ingredient.

You will find other hangover prevention products on the market that contain medicines or stimulants which may be more likely to cause side effects.

If unsure, it's always best to discuss with your doctor before taking a new supplement. This is especially important if you're taking regular medications.

Final thoughts

This guide has introduced you to the 7 best hangover supplements on the market right now. We've also done a deep dive into all the key ingredients and how to make the most of your supplements.

An important point to appreciate is that the supplements mentioned in this article are not “hangover cures”. At the very best, they can support recovery alongside sensible drinking. That means, if you drink way too much, you’ll wake up with a hangover regardless.

If you're getting to the stage in life where drinking water and getting an early night's sleep just isn't doing the trick anymore, a hangover supplement may be exactly what you need.
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